AMPK signalling
Cell studies link MOTS-c responses to AMP-activated protein kinase during metabolic stress.
Product images are for illustrative reference only. Final label layout and packaging details may vary by batch or production run. Product identity, strength and batch-specific documentation are provided separately and remain product-specific.
NOREXA PEPTIDES / RESEARCH MATERIAL
MOTS-c10 mg
Lyophilized Peptide — Single vial
MOTS-c 10 mg supplied exclusively as a laboratory research material. Available batch documentation is published only under its corresponding batch record.
Out of stock
Pricing confirmed separately
- RESEARCH FOCUS
- Metabolism & Mitochondria
QUANTITY
Research areas
FOR LABORATORY RESEARCH USE ONLY.
VERIFY BATCH →Not for human or animal consumption.
Not intended to diagnose, treat, cure or prevent any disease.
RESEARCH & TECHNICAL OVERVIEW
MOTS-c
10 mg
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. The human sequence listed in the product record is used in research on mitochondrial-to-nuclear communication and metabolic stress responses.
Research includes cell studies, animal models and emerging human observational work. Findings from experimental systems should not be read as clinical efficacy claims.
RESEARCH SCOPE
For research use only. Not for human or veterinary use. Published findings describe the compound or related research systems; they are not claims about this NOREXA batch.
HANDLING INFORMATION
Storage After
Reconstitution.
- Temperature
- Refrigerate at 2–8°C.
- Light
- Keep sealed and protected from light.
- Stability
- An exact post-reconstitution stability period has not been established for this formulation.
An exact post-reconstitution storage period has not been established for this formulation.
MedChemExpress — MOTS-c (human) technical record ↗SCIENTIFIC CONTEXT
Structured.
Source-led.
Longer technical information is grouped for easier reading on desktop and mobile.
01Natural Biological Context+
MOTS-c is described as an endogenous mitochondrial-encoded peptide. Laboratory reagents reproduce a defined sequence for controlled experiments involving cellular stress and metabolism.
02Research Mechanisms+
Mitonuclear communication
Research has observed stress-dependent nuclear translocation and changes in nuclear gene expression.
Metabolic homeostasis
Mouse studies have examined glucose handling, diet-induced metabolic phenotypes and physical performance.
03Research Applications+
- Mitochondrial signalling and metabolic-stress models.
- AMPK-dependent transcription and antioxidant-response research.
- Preclinical energy-homeostasis and physical-performance studies.
04Laboratory Research Preparation+
Lyophilized material may require preparation as a laboratory solution before use in an in-vitro assay. The solvent or buffer and working concentration should follow the applicable protocol and documentation for the exact molecular form.
This page intentionally provides no human dosing calculations, syringe-unit conversions, administration route or treatment schedule. Preparation conditions should be established and recorded by qualified laboratory personnel.
INDEPENDENT VERIFICATION
Batch evidence,
without overclaiming.
Purity alone is not enough. NOREXA distinguishes identity, purity and actual quantity, and publishes results only for the exact batch tested.
CURRENT BATCH / LOT
Independent batch verification: report not currently published
No identity, purity, quantity or batch number is shown as independently verified until exact product-and-lot evidence is available.
OPEN CENTRAL BATCH VERIFICATION →HISTORICAL BATCHES
No historical batch records are currently published for this product.
PRODUCT INFORMATION
Technical
Data.
Verified identity and catalogue information for this NOREXA research material. Unconfirmed fields are omitted.
- Product Name
- MOTS-c
- Content
- 10 mg
- Form
- Lyophilized Peptide
- Presentation
- Single vial
- CAS Number
- 1627580-64-6
- Peptide Sequence
- MRWQEMGYIFYPRKLR
- Molecular Formula
- C101H152N28O22S2
- Molecular Weight
- 2174.6 g/mol
- Research Classification
- Research Use Only
Batch documentation and independent reports are shown only when published for the exact corresponding batch.
CHEMICAL IDENTITY REFERENCE ↗SELECTED SOURCES
Research
Literature.
Selected literature describes the compound and relevant research pathways; it does not constitute testing or endorsement of this NOREXA batch.
- 01Preclinical↗
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Cell Metabolism · 2015
- 02In vitro↗
The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression
Cell Metabolism · 2018
- 03Preclinical↗
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Nature Communications · 2021
PRODUCT FAQ
MOTS-c
questions.
01What is MOTS-c?+
MOTS-c is a short peptide encoded within mitochondrial DNA and studied as part of mitochondrial-to-nuclear signalling.
02Does MOTS-c occur naturally?+
Published research describes endogenous MOTS-c; the vial is a synthetic laboratory reagent corresponding to a defined research sequence.
03What storage statement is shown?+
Only the aqueous laboratory-stock condition published for a reference matching the displayed CAS number, formula and sequence. No bacteriostatic-water refrigerator period is inferred.
04Are the cited findings clinical claims?+
No. Much of the mechanism work is cellular or preclinical, and the citations do not test this NOREXA batch.
SECTION 01 — STANDARDS
Scientific transparency,
documented for research.
01 / 03Scientific Integrity
Independent analytical results are presented as reported by the testing laboratory, without altering the laboratory’s findings.
02 / 03Batch Traceability
Each batch is assigned a record linking the product to its available technical and independent testing documentation.
03 / 03Quality Documentation
Available batch documentation is organized under the corresponding batch number for clear reference.